Table 4.
Concentration of triacylglycerol in livers and gastrocnemius muscles of overnight-fasted wild type (WT) and PDK4 knockout (PDK4 KO) mice fed a HSF diet with and without clofibric acid
| Genotype | Clofibric acid |
Liver | Gastrocnemius |
|---|---|---|---|
| mg/g wet weight | |||
| WT | − | 235 ± 18 | 90 ± 8 |
| WT | + | 114 ± 24*† | 49 ± 8* |
| PDK4 KO | − | 185 ± 9* | 64 ± 7* |
| PDK4 KO | + | 72 ± 11 *† | 33 ± 5*† |
Data are presented as mean ± S.E., n = 6 for wild type and PDK4 knockout mice fed on a HSF diet with and without clofibric acid. Concentration of triacylglycerol was measured as described in the Materials and Methods section.
P < 0.05 relative to non-treated wild type mice.
P < 0.05 relative to non-treated PDK4 knockout mice.