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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Exp Neurol. 2011 Dec 29;235(1):162–173. doi: 10.1016/j.expneurol.2011.12.037

Table 5. Changes in gene expression after mesopram and control infusions compared to naïve control animals (pFDR<0.05).

Numbers indicate probe sets changing at the criteria indicated. Numbers in parentheses indicate the number of significantly upregulated (+) and down regulated (−) probe sets. Percentage numbers in column 3 and 4 represent the percentage of probe sets changed at the criteria indicated (>1.2-fold and >2-fold). Detailed data for each probe set can be found in Supplementary Table 3. Significant changes were determined at p<0.05 at a false discovery rate of 5%.

Group # significantly changed probe sets # of probe sets with > 20% change # of probe sets with > 100% change
Any Day 544 520 36
Mesopram infusion Day 1 524 (+ 275 ; −249) 500 (+ 261; −239) (95.4%) 35 (+ 21; −14) (6.7%)
Mesopram infusion Day 3 14 (+ 6; −8) 14 (+6; −8) (100%) 2 (+ 1; −1) (14.2%)
Mesopram infusion Day 7 9 (+ 5; −4) 9 (+5; −4) (100%) 3 (+ 2; −1) (33.3%)
Mesopram infusion Day 14 18 (+7; −11) 18 (+ 7; −11) (100%) 1 (+ 0; −1) (5.6%)
Control infusion Day 7 8 (+2; −6) 8 (+ 2; −6) (100%) 1 (+ 0; −1) 12.5%