Table III.

miRNAs in the signature predictive of stage I NSCLC

miRNAs	P-value	FDR	Hazard ratio	miRNAs	P-value	FDR	Hazard ratio
Signature independent of cancer subtype
HS_215	1.54× 10−9	0.000000672	0.61 (0.52-0.72)	solexa-3044-295	0.0014	0.0029	0.71 (0.58–0.88)
solexa-826-1288	1.35 × 10−7	0.00000611	0.48 (0.37–0.63)	HS_188	0.0015	0.0029	0.67 (0.52-0.86)
hsa-miR-888	3.36× 10−7	0.00000946	0.36 (0.25-0.54)	HS_303_a	0.0017	0.0033	1.82 (1.25–2.65)
HS_142.1	1.16 × 10−5	0.0000783	0.49 (0.36–0.68)	hsa-miR-519e	0.0017	0.0033	0.46 (0.29–0.75)
hsa-miR-1207-3p	4.54 × 10−5	0.000226	0.55 (0.41–0.73)	hsa-miR-124	0.002	0.0037	0.77 (0.65–0.91)
hsa-miR-603	0.000057	0.00027	0.68 (0.57–0.82)	hsa-miR-941	0.0036	0.0063	1.38 (1.11–1.72)
hsa-miR-769-3p	0.0001	0.0004	0.76 (0.66–0.87)	hsa-miR-34a	0.0038	0.0065	1.63(1.17–2.26)
HS_6	0.0004	0.0012	0.72 (0.6–0.86)	hsa-miR-494	0.0038	0.0066	0.82 (0.72–0.94)
hsa-miR-31*	0.0004	0.0012	1.21 (1.09–1.35)	hsa-miR-222	0.0042	0.0069	1.5 (1.14–1.98)
hsa-miR-892b	0.0004	0.0011	0.52 (0.36-0.74)	hsa-miR-34a*	0.0044	0.0072	1.23 (1.07-1.43)
HS_15.1	0.0006	0.0016	0.62 (0.47–0.82)	hsa-miR-205	0.0048	0.0077	0.85 (0.77–0.95)
HS_231	0.0006	0.0014	0.55 (0.4–0.78)	hsa-miR-151-5p	0.0049	0.0077	1.53 (1.14–2.05)
hsa-miR-185*	0.0008	0.0018	0.67 (0.53–0.85)	solexa-9124-90	0.0053	0.008	0.6 (0.42–0.86)
hsa-miR-425	0.0008	0.0018	2.04(1.35-3.09)	hsa-miR-132	0.0054	0.0081	1.38 (1.1–1.72)
hsa-miR-615-5p	0.0008	0.0019	0.5(0.33-0.75)	hsa-miR-192*	0.0055	0.0083	1.32 (1.08–1.6)
hsa-miR-940	0.001	0.0023	0.56 (0.39–0.79)	hsa-miR-455-3p	0.0059	0.0086	1.29 (1.08–1.54)
hsa-miR-512-5p	0.0012	0.0025	0.61(0.46-0.82)	HS_122.1	0.0066	0.0094	0.4 (0.2–0.77)
Signature of ADC
hsa-miR-615-5p	0.000024	0.00596	0.30 (0.17–0.52)	HS_285	0.005	0.028	0.42 (0.23–0.77)
hsa-miR-34b	0.0000699	0.00683	0.65 (0.52–0.8)	hsa-miR-377*	0.005	0.0281	0.53 (0.34–0.83)
has-miR-1248	0.0000875	0.00743	0.65 (0.53–0.81)	hsa-miR-588	0.0058	0.0292	0.53 (0.34–0.83)
HS_59	0.0001	0.0078	0.46 (0.31–0.69)	hsa-miR-34c-5p	0.0082	0.0349	0.78 (0.64–0.94)
HS_283_a	0.0002	0.0084	0.39 (0.24–0.64)	HS_47	0.0092	0.0363	0.41 (0.21–0.8)
hsa-miR-34c-3p	0.0002	0.008	0.66 (0.53–0.82)	HS_43.1	0.0106	0.0381	0.58 (0.39–0.88)
hsa-miR-512-3p	0.0005	0.0118	0.41 (0.25–0.68)	hsa-miR-512-5p	0.0125	0.0401	0.58 (0.38–0.89)
HS_78	0.0014	0.0176	0.63 (0.47–0.83)	HS_74	0.0147	0.0441	0.77 (0.62–0.95)
hsa-miR-34b*	0.0014	0.0177	0.77 (0.66–0.91)	hsa-miR-658	0.0163	0.0454	0.60 (0.40–0.91)
hsa-miR-934	0.0022	0.0213	0.41 (0.23–0.72)	hsa-miR-548b-3p	0.0174	0.0459	0.66 (0.47–0.93)
HS_60	0.0036	0.0263	0.49 (0.31–0.79)	HS_142.1	0.0176	0.046	0.58 (0.36–0.91)
hsa-miR-572	0.0041	0.0267	0.65 (0.48–0.87)	hsa-miR-425	0.019	0.0463	2.26 (1.14–4.46)
hsa-miR-662	0.0044	0.0272	0.61 (0.44–0.86)	hsa-miR-1255a	0.0209	0.0479	0.58 (0.36–0.92)
HS_187	0.0045	0.0272	0.52 (0.33–0.82)
Signature of SCC
hsa-miR-888	0.0000178	0.00477	0.15 (0.07–0.36)	HS_159	0.00431	0.02569	0.39 (0.20–0.74)
hsa-miR-801:9.1	0.000019	0.00564	0.37 (0.24–0.59)	HS_188	0.00451	0.0263	0.47 (0.28–0.79)
HS_215	0.00011	0.00756	0.54 (0.39–0.74)	hsa-miR-671:9.1	0.00686	0.03481	0.65 (0.47–0.89)
HS_197	0.00031	0.0088	0.18 (0.07–0.46)	HS_65	0.00741	0.03612	0.56 (0.37–0.86)
HS_263.1	0.00035	0.00884	0.12 (0.04–0.39)	hsa-miR-193a-3p	0.00785	0.03736	1.82 (1.17–2.82)
HS_83.1	0.00036	0.00886	0.23 (0.10–0.52)	solexa-499-2217	0.00795	0.03798	0.20 (0.06–0.66)
hsa-miR-892b	0.00091	0.01183	0.30 (0.15–0.61)	hsa-miR-595	0.01025	0.04503	0.42 (0.21–0.81)
hsa-miR-939	0.00115	0.01254	0.10 (0.02–0.39)	hsa-miR-34a*	0.01032	0.04507	1.52 (1.10–2.11)
hsa-miR-1180	0.00362	0.02325	0.50 (0.32–0.8)

Italic were overlapped miRNAs in the signature of ADC. Bold were also in the signature of SCC.