Table IV.
Results for SNP rs2930961 on RAD54B gene using unconditional logistic regression
Stratum | Sample size |
C/T versus T/T genotype |
C/C versus T/T genotype |
Log-additive model |
P | ||||
Cases | Controls | OR | 95% CI | OR | 95% CI | OR | 95% CI | ||
Smoking status | |||||||||
Never-smokers | 255 | 1613 | 0.79 | 0.59–1.05 | 0.43 | 0.25–0.73 | 0.71 | 0.71–0.87 | |
Ever-smokers | 2366 | 2535 | 1.11 | 0.98–1.25 | 1.13 | 0.94–1.36 | 1.08 | 0.99–1.17 | |
Interaction | 1.52 | 1.21–1.90 | 2.31 × 10−4 |
CI, confidence interval; P, P-value for rs2930961 × tobacco interaction adjusting on study, age, sex and pack-years (coded quantitatively).