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. 2012 Apr 24;3:66. doi: 10.3389/fgene.2012.00066

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Copyright © 2012 Crawford and Lazzaro.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited.

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Figure A3 — The power to detect selective sweeps before and after simulated next-generation sequencing. The proportion of statistically significant detections of positive selection was calculated from simulations of a 30-kb region of 30 chromosomes with one selective sweep. Simulations were compared to a null distribution generated by neutral simulations and considered significant at 0.05 cutoff. The top panel shows the results for recent selective sweep models (τ = 0.005) and the bottom panel shows results for models with relatively older selective sweeps (τ = 0.01). “Pre-seq” refers to the complete sequence information, without simulated next-generation sequencing and SNP calling.