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LRP-ApoE interactions modulate glutamate induction of βAPP. NTera2 cells were treated with 20 μM glutamate in the presence or absence of 200 nM receptor-associated protein (RAP); additional cultures were treated with RAP alone. βAPP expression was determined 20 hours later by Western blot analysis. *p < 0.05; **p < 0.01; #p < 0.05 (vs. RAP alone).
