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Effects of tensile strain and Wnt3A, separately or combined, on catabolic proteinase transcription in chondrocytes. Untreated chondrocytes served as controls. (A) MMP3, (B) MMP13, (C) ADAMTS-4 and (D) ADAMTS-5 gene expression levels analysed immediately or (E), (F), (G) and (H) following a four-hour recovery period respectively (refer to Figure 2 for calculations and statistical significance).
