Table 1.
Baseline (before starting IFX) | |
---|---|
Female, age (mean ± SD, range) | 91/111 (82%), 51.6 ± 13.3 years (21 ~ 80) |
Disease duration (mean ± SD, range) | 6.6 ± 6.4 years (4 months ~ 32 years) |
DAS28 (ESR) (mean ± SD, range) | 5.37 ± 1.33 (1.71 ~ 8.41) |
MTX (mean ± SD, range) | (used in all the patients), 8.1 ± 1.6 mg/week (4 ~ 14 mg) |
Corticosteroids users | 68/111 patients (61%) |
PSL dosage (mean ± SD, range) | 6.2 ± 3.2 mg/day (2 ~ 16 mg) |
At the study point | |
Total number of IFX (mean ± SD, range) | 13.0 ± 7.3 times (3 ~ 38) |
DAS28(ESR) (mean ± SD, range) | 3.55 ± 1.64 (0.54 ~ 7.84) |
EULAR response | Good response 55% (including remission 38%) |
Moderate response 18% | |
NOR 27% (including LOR 21%) | |
Discontinuation | 45/111 (41%) |
Reasons for discontinuation | Remission, eight; NOR, 21; adverse events, 14; |
financial reasons, two |
IFX, infliximab; LOR, loss of response; MTX, methotrexate; NOR, no response; PSL, prednisolone.