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. 2012 Mar 15;9:53. doi: 10.1186/1742-2094-9-53

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Copyright ©2012 Tauchi et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Immunofluorescence analysis after SCI. 5-HT staining of the ventral horn (A-C, 5 mm distal to the lesion) is shown for the ADAMTS-4 treatment group (A and B) and vehicle group (C). Higher-magnification of the boxed area in A is shown in B. The arrows in B and C indicate 5-HT-positive fibers. Scale bars, 500 μm (A) and 50 μm (B and C). (D) The 5-HT-positive areas are summarized in the graph. Five rats are used for each group at eight weeks after spinal cord injury. *, P < 0.05. Values are presented as the means ± SD. 5-HT, 5-hydroxytryptamine; SCI, spinal cord injury.