Table 3.
Correlation between serum endocannabinoids and blood pressure in minor versus major depression
| AEA | 2-AG | ||||
|---|---|---|---|---|---|
| r* | P† | r | P | ||
| Minor depression n = 12 | MAP | .44 | 0.15 | .44 | 0.15 |
| SBP | .36 | 0.25 | .22 | 0.49 | |
| DBP | .30 | 0.34 | .71 | < 0.01‡ | |
| HR | .57 | 0.05‡ | .11 | 0.74 | |
| Major depression n = 16 | MAP | .48 | 0.06 | -.20 | 0.47 |
| SBP | .21 | 0.43 | -.23 | 0.40 | |
| DBP | .54 | 0.03‡ | -.30 | 0.26 | |
| HR | -.06 | 0.84 | -.22 | 0.41 | |
In the same cohort of females, serum AEA is significantly increased in minor depression, whereas 2-AG is decreased in major depression 11. * correlation coefficient as determined by Pearson correlation tests; † probability value; ‡ statistical significance; MAP, mean arterial blood pressure; SBP, systolic blood pressure; DBP, diastolic blood pressure; HR: heart rate