Table 2.
Comparison of haemodynamic parameters between responders and nonrespondersa
| Parameters | Responders (n = 13) | Nonresponders (n = 12) | P values |
|---|---|---|---|
| HR (bpm) | |||
| Baseline | 95 (82 to 106) | 95 (81 to 104) | 0.95 |
| PLR | 95 (76 to 104) | 91 (77 to 106) | 0.95 |
| Volume expansion | 93 (78 to 105) | 96 (79 to 106) | 0.72 |
| SAP (mmHg) | |||
| Baseline | 108 (99 to 121) | 105 (92 to 115) | 0.47 |
| PLR | 117 (93 to 121) | 107 (86 to 120) | 0.46 |
| Volume expansion | 120 (111 to 130)b,c | 107 (99 to 126) | 0.2 |
| DAP (mmHg) | |||
| Baseline | 59 (49 to 71) | 57 (46 to 70) | 0.62 |
| PLR | 61 (44 to 67) | 61 (44 to 70) | 1 |
| Volume expansion | 67 (49 to 72)b, c | 56 (50 to 70) | 0.51 |
| MAP (mmHg) | |||
| Baseline | 77 (65 to 84) | 75 (62 to 83) | 0.62 |
| PLR | 77 (61 to 84) | 72 (58 to 84) | 0.64 |
| Volume expansion | 83 (71 to 90)b, c | 71 (67 to 87) | 0.27 |
| CVP (mmHg) | |||
| Baseline | 7 (5 to 13) | 11 (8 to 15) | 0.08 |
| PLR | 12 (8 to 14)b | 12 (10 to 13) | 0.68 |
| Volume expansion | 12 (10 to 15)b | 13 (10 to 17)b | 0.46 |
| ΔrespPP (%) | |||
| Baseline | 6 (4 to 8) | 7 (4 to 10) | 0.59 |
| PLR | 6 (4 to 7) | 9 (5 to 11) | 0.14 |
| Volume expansion | 5 (4 to 8) | 7 (5 to 10) | 0.11 |
| VTI (cm/second) | |||
| Baseline | 20 (15.2 to 25) | 16.1 (13.7 to 21.6) | 0.3 |
| PLR | 24.7 (17.7 to 28.3)b | 15.8 (12.9 to 22.3) | 0.03 |
| Volume expansion | 25.4 (19.1 to 30)b, c | 16 (14 to 21.4) | < 0.001 |
| SV (mL) | |||
| Baseline | 72 (50 to 88) | 55 (49 to 84) | 0.7 |
| PLR | 86 (59 to 99)b | 58 (48 to 85) | 0.1 |
| Volume expansion | 89 (66 to 109)b, c | 60 (48 to 82) | 0.02 |
| CO (L/minute) | |||
| Baseline | 5.8 (4 to 8.3) | 5.6 (4.3 to 7.8) | 0.96 |
| PLR | 5.9 (4.7 to 9.6)b | 5.8 (4 to 6.6) | 0.27 |
| Volume expansion | 7.5 (5.2 to 10.1)b, c | 5.2 (4.4 to 7.7) | 0.03 |
aPLR, passive leg raising; HR, heart rate; SAP, systolic arterial pressure; DAP, diastolic arterial pressure; MAP, median arterial pressure; CVP, central venous pressure; ΔrespPP, respiratory pulse pressure variation; VTI, velocity time integral of aortic blood flow; SV, stroke volume; CO, cardiac output. bP < 0.05 vs baseline; cP < 0.05 vs PLR. Values are medians (25th to 75th interquartile ranges).