Table 3.
Univariate and multivariate logistic regression analysis used to differentiate survivors and non-survivors
| Univariate (n = 66) | Multivariate (n = 66) | ||||||
|---|---|---|---|---|---|---|---|
| OR | 95% CI | P value | OR | 95% CI | P value | ||
| Gender | Male | 1.00 | - | - | |||
| Female | 5.22 | 1.25-21.82 | 0.023 | 8.19a | 0.75-89.05 | 0.084 | |
| 4.56b | 0.65-31.81 | 0.126 | |||||
| 5.47c | 1.15-25.99 | 0.033 | |||||
| Age, years | ≤62 | 1.00 | - | - | |||
| > 62 | 2.51 | 0.59-10.69 | 0.214 | ||||
| APACHE II score |
≤18 | 1.00 | - | - | |||
| > 18 | 2.53 | 0.63-9.89 | 0.192 | ||||
| SOFA score | ≤7 | 1.00 | - | - | |||
| > 7 | 2.02 | 0.48-8.63 | 0.341 | ||||
| ΔmHLA-DR3 | > 4.8 | 1.00 | - | - | - | ||
| ≤4.8 | 75.00 | 8.04-699.44 | < 0.001 | 94.71a | 7.64-1174.27 | < 0.001 | |
| ΔmHLA-DR7 | > 9 | 1.00 | - | - | |||
| ≤9 | 54.00 | 5.99-486.08 | < 0.001 | 51.04b | 5.35-486.94 | < 0.001 | |
| ΔmHLA-DR7-3 | > 3.5 | 1.00 | |||||
| ≤3.5 | 7.20 | 1.39-37.23 | 0.019 | 7.46c | 1.34-41.39 | 0.022 | |
aΔmHLA-DR3, bΔmHLA-DR7, and cΔmHLA-DR7-3 were entered into multivariate logistic regression model separately with adjustment of gender. ΔmHLA-DR3 and ΔmHLA-DR7 were defined as the value change in mHLA-DR on days 3 and 7 compared with that on day 0, and ΔmHLA-DR7-3 was defined as the value change in mHLA-DR on day 7 compared with that on day 3. APACHE II, Acute Physiology and Chronic Health Evaluation II; CI, confidence interval; OR, odds ratio; SOFA, Sequential Organ Failure Assessment.