Table 1.
Characteristics of healthy controls and non surviving critically ill patients
| Healthy controls |
Critically ill patients: postmortem biopsies |
|
|---|---|---|
| Number | 20 | 61 |
| Gender (no. male) | 14 | 36 |
| Age (yr) (mean ± SD) | 70 ± 12 | 67 ± 15 |
| BMI (kg/m2) (mean ± SD) | 25.0 ± 2.6 | 24.1 ± 3.5 |
| History of diabetes (no.) | 3 | 9 |
| APACHE-II score on admission (median (IQR)) | - | 26 (20 to 34) |
| Admission diagnose | - | |
| - Cardiovascular | 5 | |
| - Gastrointestinal or liver | 5 | |
| - Hematologic or oncologic | 10 | |
| - Neurologic | 3 | |
| - Renal | 2 | |
| - Respiratory | 30 | |
| - Other | 6 | |
| ICU stay (median (IQR)) | 0 | 10 (6 to 19) |
| Cause of death in ICU | - | |
| - Severe brain damage | 2 | |
| - Respiratory failure | 26 | |
| - Therapy resistant septic shock/cardiovascular collapse | 14 | |
| - Persistent MOF after septic or SIRS induced shock | 19 |
APACHE II, Acute Physiology and Chronic Health Evaluation II; BMI, body mass index; ICU, intensive care unit; IQR, interquartile range; MOF, multiple organ failure; SD, standard deviation; SIRS, systemic inflammatory response syndrome; Yrs, years.