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. Author manuscript; available in PMC: 2013 Apr 19.
Published in final edited form as: Cell Host Microbe. 2012 Apr 19;11(4):364–374. doi: 10.1016/j.chom.2012.02.007

Figure 4. Mutating ToxA or removing the C. elegans diphthamide modification inhibits ToxA-mediated lethality.

Figure 4

(A) Lifespan comparison of pmk-1(km25) mutants fed either wild-type ToxA, the catalytic mutant ToxAE575Δ, or vector control food. (B) Lifespan comparison between wild-type N2 and diphthamide synthesis mutants when fed ToxA following pmk-1 RNAi. All assays were started with L4 stage animals.