Table 4. Cortico-striatal and thalamo-striatal parameters.
NMDAR/AMPAR | GluN2B/NMDAR | Distance from soma | |||||
Smeal et al., 2008 | Ctx | 1.52 | ↓ | Ctx | τ = 116.5 ms | ↑ | Ctx more proximal |
Th | 2.6 | ↑ | Th | τ = 96.5 ms | ↓ | Th more distal | |
Ding et al., 2008 | Ctx | 2.75 | ↑ | Ctx | 0.25 | ↓ | –Not Addressed– |
Th | 2.04 | ↓ | Th | 0.42 | ↑ | –Not Addressed– |
Ctx = cortico-striatal synapses; Th = thalamo-striatal synapses. τ = decay time constant for NMDA current. Arrows represent a relative increase or decrease in NMDA/AMPA ratio or GluN2B/NMDA ratio between cortico-striatal and thalamo-striatal synapses for each study.