Table 1. Transcription factor mutants defective in hyphal maintenance in rapamycin.

Gene name	Description*	Germ tube formation in YPD	Hyphal elongation in YPD+rapamycin
Wild type		+ + + + +	+ + + + +
NTO1	Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3	+ + + + +	+ + +
GIS2	Putative transcription factor; expression is increased in high iron and reduced upon yeast-hyphal switch; null mutant exhibits sensitivity to sorbitol, 5-fluorocytosine, and cold temperatures	+ + + + +	+ + +
ASH1	GATA-like transcription factor; localizes to nuclei of daughter cells and hyphal tip cells; mRNA localization is mediated by binding to She3p; required for wild-type virulence and filamentous growth	+ + + + +	+ + +
BRG1	Putative DNA-binding transcription factor; similar to S. cerevisiae Gat2p; transposon mutation affects filamentous growth	+ + + + +	+
ASG1	Gal4p family zinc-finger transcription factor with similarity to S. cerevisiae Asg1p	+ + + + +	+ +
ROB1	Putative protein of unknown function; null mutant displays abnormal colony morphology and invasive growth; caspofungin repressed	+ + +	+
AHR1	Zinc-finger transcription factor involved in regulation of adhesion genes; involved in white-opaque switch; forms complex with Mcm1p; null mutant displays sensitivity to 5-fluorocytosine and to lithium chloride	+ +	+
BCR1	C2H2 zinc finger transcription factor required for wild-type biofilm formation; mutation affects filamentous growth; regulates cell-surface-associated genes; filament induced; Tup1p-, Tec1p-, Mnl1p-regulated; mRNA binds to She3p	+ + +	+ +

*: All descriptions are from the Candida Genome Database. + indicates levels of filamentation.