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(A) In the normal control, 661W had a flattened appearance with few intercellular spaces. (B) After light exposure, the cells became spindled with large intercellular spaces. (C–E) 661W photoreceptors underwent apoptosis, as determined by TUNEL assay. (F) Statistical analysis showed that the TUNEL positivity was significantly increased at 0 hour, 24 hours and 48 hours after light exposure.
