Table 1. Mean and Median Bias Analysis of Pima Capillary and Venous Measurements.
Comparison | Reference method* (cells/µl) | Number of pairs (%) | Mean Bias (95%CI) | Median Bias (IQR) | P-value** |
Pima CD4 Capillary | Overall | 176 | −66.3(−83.4, −49.2) | −41.0(−105.0, 4.5) | <0.001 |
0–250 | 27 | −10.8(−27.3, 5.6) | −6.0 (−32.0, 11.0) | 0.198 | |
250–500 | 90 | −47.3(−62.2, −32.5) | −40.5 (−76, −5.0) | <0.001 | |
>500 | 59 | −120.6 (−162.8, −78.4) | −107.0 (−197.0, −10.0) | <0.001 | |
Pima CD4 Venous | Overall | 206 | −68.5 (−79.6, −57.4) | −54.0 (−95.0, −17.0) | <0.001 |
0–250 | 35 | 13.6 (2.5, 24.7) | −16.0 (−35.0, −1.0) | 0.020 | |
250–500 | 107 | −54.6 (−64.5, −44.7) | −53.0 (−79.0, −23.0) | <0.001 | |
>500 | 64 | −121.7 (−147.9, −95.4) | −93.5 (−167.5, −64.5) | <0.001 |
BD FACSCalibur.
P-value using Wilcoxon Signed Rank Test.
CI = confidence interval, CD4 = CD4+ T cell count (cells/µL).