Table 3. Sensitivity, specificity, negative predictive value, and positive predictive value of the Pima CD4 test (finger stick and venous) compared to the reference method BD FACSCalibur.
Pima CD4 Test | Sensitivity (95%CI) | Specificity (95%CI) | NPV (95%CI) | PPV (95%CI) |
Finger stick <250 cells/µl | 0.963 (0.791−0.998) | 0.866 (0.798−0.914) | 0.992 (0.951−0.999) | 0.565 (0.412−0.708) |
Finger stick <300 cells/µl | 0.932 (0.803−0.982) | 0.795 (0.715−0.859) | 0.972 (0.915−0.993) | 0.603 (0.477−0.717) |
Venous <250 cells/µl | 0.943 (0.795−0.990) | 0.854 (0.789−0.901) | 0.986 (0.947−0.998) | 0.569 (0.433−0.696) |
Venous <300 cells/µl | 0.982 (0.892−0.999) | 0.753 (0.675−0.818) | 0.991 (0.945−0.999) | 0.598 (0.490−0.697) |
CI = confidence interval, NPV = negative predictive value, PPV = positive predictive value.