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. 2012 Apr 20;7(4):e35630. doi: 10.1371/journal.pone.0035630

Table 2. Km and Vmax values for PKCε activating and inhibiting VHHs.

PKCε with activators PS and DOG (n≥3) PKCε without activators PS and DOG (n≥3) Catalytic domain (n≥2)
Km (µM) Vmax Km (µM) Vmax Km (µM) Vmax
Control 424 141 449 139 130 120
A10 348 253 352 263 no effect no effect
C1 81 191 105 139 no effect no effect
D1 126 158 137 208 no effect no effect
E6 17 29 5.1 24 n/a 6.7
G8 260 113 121 71 158 43