Table 1. Somatic mutations identified in 3′-untranslated regions of candidate mRNAs.

Gene	Nucleotide change1	MicroRNA binding affected by mutation	Predictive algorithm	Sample ID
AKT2	c.*892C>T	hsa-miR-429	DIANA-microT [47], [48]	P1768
CTNNB1	c.*538T>A	hsa-miR-640 2	miRanda [49]	P0511
		hsa-miR-10a	miRanda
		hsa-miR-587	miRanda
EGFR	c.*101C>G	-	-	IC151
ERBB2	c.*460G>C	hsa-miR-495	miRanda	P5514
		hsa-miR-630 2	microCOSM Targets [40]

¹Nucleotide changes are described relative to the following sequences: AKT2 NM_001626.3; CTNNB1 NM_001904.3; EGFR NM_005228.3; ERBB2 NM_004448.2.

²Indicates that the somatic mutation occurs within the microRNA-mRNA interaction at the seed region.