Table 2. Association study for LDA using SNPs within motilin for 1,136 German Holstein cows.
SNP | MAF allele | MAF | OR per allele (95% CI) | OR among homozygotes | PIC | HET | P | ||||
Cases | Controls | gt | allele | hom | strat | ||||||
(n = 601) | (n = 535) | (95% CI) | (−log10) | (−log10) | (−log10) | (−log10) | |||||
FN298674:g.62G>A | A | 0.49 | 0.39 | 1.47 (1.23–1.72) | 2.27 (3.22–1.59) | 0.37 | 0.47 | 4.8 | 5.1 | 5.4 | 3.3 |
FN298674:g.90T>C | T | 0.44 | 0.55 | 0.64 (0.54–0.76) | 0.40 (0.28–0.56) | 0.37 | 0.48 | 7.0 | 6.8 | 6.8 | 3.8 |
FN298674:g.1891insG | insG | 0.55 | 0.42 | 1.71 (1.44–2.02) | 2.82 (2.01–3.95) | 0.37 | 0.46 | 8.2 | 9.3 | 9.0 | 3.7 |
FN298674:g.2045C>G | G | 0.52 | 0.40 | 1.62 (1.36–1.93) | 2.44 (1.74–3.42) | 0.37 | 0.40 | 6.6 | 7.1 | 6.7 | 3.2 |
FN298674:g.4942insT | wt | 0.35 | 0.47 | 0.61 (0.51–0.72) | 0.41 (0.29–0.6) | 0.35 | 0.41 | 7.0 | 7.4 | 5.8 | 2.9 |
FN298674:g.6689C>T | T | 0.28 | 0.40 | 0.57 (0.45–0.72) | 0.36 (0.22–0.57) | 0.32 | 0.34 | 4.3 | 5.6 | 5.0 | 1.6 |
FN298674:g.6728G>A | A | 0.28 | 0.40 | 0.57 (0.45–0.72) | 0.36 (0.22–0.57) | 0.32 | 0.34 | 4.3 | 5.6 | 5.0 | 1.6 |
For each SNP, minor allele frequencies (MAF), the MAF allele, odds ratios (OR) with their 95% confidence intervals (CI), polymorphism information content (PIC), and heterozygosity (HET) are given. Furthermore, −log10P-values (P) are given for genotype (gt), allele, among homozygotes (hom) and for genotype after correcting the data for stratification (strat).