Table 2. siRNA targets.
OGS | degree of target knockdown (relative to the median array) | % reduction in expression | Batch |
ABL1 | −2.01 | 50% | KD2 |
AKT1 | −2.79 | 64% | KD2 |
CCNA2 | −2.87 | 65% | KD2 |
CCNB1 | −2.84 | 65% | KD2 |
CCNB2 | −3.96 | 75% | KD3 |
CCND3 | −2.91 | 66% | KD2 |
CDC16 | −2.98 | 66% | KD2 |
CDC2 | −2.72 | 63% | KD1 |
CDC25B | −2.08 | 52% | KD1 |
CDC37 | −2.17 | 54% | KD2 |
CDK2 | −2.6 | 62% | KD2 |
CDK4 | −3.42 | 71% | KD2 |
CDK7 | −2.53 | 60% | KD1 |
CDKN2C | −2.37 | 58% | KD2 |
CEBPD | −2.02 | 50% | KD2 |
CEBPZ | −2.96 | 66% | KD2 |
CHEK1 | −2.8 | 64% | KD2 |
CTNNB1 | −2.19 | 54% | KD1 |
ETS1 | −1.98 | 49% | KD3 |
FOXM1 | −2.69 | 63% | KD2 |
FOXO3A | −2.72 | 63% | KD1 |
GABARAP | −3.6 | 72% | KD2 |
HDAC2 | −2.84 | 65% | KD2 |
HDAC3 | −2.77 | 64% | KD2 |
HSF2 | −4.62 | 78% | KD1 |
MAP2K1 | −3.44 | 71% | KD2 |
MAPK1 | −2.05 | 51% | KD2 |
MCM2 | −5.96 | 83% | KD3 |
MITF | −14.51 | 93% | KD3 |
NCOR2 | −2.32 | 57% | KD2 |
NMI | −4.77 | 79% | KD2 |
PCNA | −2.7 | 63% | KD1 |
PIAS1 | −3.04 | 67% | KD3 |
PIK3CB | −2.15 | 53% | KD2 |
RB1 | −4.34 | 77% | KD1 |
RBL2 | −2.53 | 60% | KD2 |
RELA | −2 | 50% | KD2 |
SKP2 | −3.4 | 71% | KD2 |
SP1 | −1.99 | 50% | KD3 |
SP100 | −3.06 | 67% | KD2 |
STAT1 | −3.29 | 70% | KD2 |
STAT3 | −5.75 | 83% | KD3 |
STAT6 | −2.21 | 55% | KD2 |
TCEA1 | −3.04 | 67% | KD1 |
TP53 | −2.74 | 64% | KD1 |
‘OGS’ designates the official gene symbol of the target mRNA, ‘Degree of knockdown’ is the fold reduction in expression of the target RNA after siRNA incubation relative to median expression of the target RNA in all microarrays, ‘% reduction in expression’ is the % that the target RNA expression is reduced relative to median expression of the target RNA in all other microarrays, and ‘Batch’ is the experimental batch in which the siRNA was used.