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Influence of fluid percussion injury (FPI) on cerebrospinal fluid (CSF) Endothelin-1 (ET-1) in (A) male and (B) female pigs. Conditions are: before (0 time) and 1 h after FPI; in vehicle (FPI), phenylephrine (Phe) pre- and post-treated animals. Pre-treatment is 30 min before whereas post-treatment is 30 min after FPI, n=5. *p<0.05 compared with corresponding before FPI value; +p<0.05 compared with corresponding untreated FPI value; #p<0.05 compared with corresponding female value.
