FIG. 3.
Influence of papaverine (10−8, 10−6 M) on pial artery diameter in the absence and presence of fluid percussion injury (FPI) in (A) male and (B) female pigs. Conditions are: before (sham control) and 1 h after FPI; in vehicle (FPI), phenylephrine (Phe), and Phe+BQ-123 (1 mg/kg i.v.) pre- and post-treated animals. Pre-treatment is 30 min before whereas post-treatment is 30 min after FPI, n=5. *p<0.05 compared with corresponding before FPI value; +p<0.05 compared with corresponding untreated FPI value; #p<0.05 compared with corresponding female value.