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. 2012 Apr 23;7(4):e35496. doi: 10.1371/journal.pone.0035496

Table 1. Comparison of admission characteristics upon hospitalization between patients with not-impaired or impaired admission eGFR.

Characteristics Total Cohort (n = 828) a-eGFR≥60 (n = 447) a-eGFR<60 (n = 381) p-value**
Age (y) 65 (54–74) 59 (49–71) 70 (61–75) <0.001
Male 65.5% 72.0% 57.7% <0.001
History of hypertension 69% 57.9% 81.9% <0.001
Current smoker 36.7% 44.5% 27.6% <0.001
History of diabetes 25.7% 19.2% 33.3% <0.001
Previous PCI 8.8% 6.7% 11.3% 0.021
Previous CABG 8.5% 5.1% 12.3% <0.001
Prior CAD (stenosis >50%) 15.5% 10.7% 21.0% <0.001
Previous AMI 16.3% 12.3% 21.0% 0.001
Prior use of ACEI/ARB* 41.7% 31.1% 54.1% <0.001
STEMI 50.2% 55.9% 43.6% <0.001
aSBP<100 mm Hg 6.3% 3.6% 9.5% 0.001
aHR (beats/min) 80 (70–95) 80 (70–92) 80 (70–100) 0.249
aHR >100 beats/min 16.5% 13.2% 20.5% 0.005
Killip class >1 20.9% 15.6% 28.9% 0.001

a-eGFR, admission estimated glomerular filtration rate (mL/min/1.73 m2); PCI, percutaneous coronary intervention; CABG, coronary artery bypass graft; CAD, coronary artery disease; AMI, acute myocardial infarction; ACEI, angiotensin-converting enzyme inhibitors; ARB, angiotensin II receptor blockers; STEMI, ST elevation myocardial infarction; aSBP, admission systolic blood pressure; aHR, admission heart rate. Continuous variables are presented as median values (with interquartile ranges). Categorical variables are presented as percentages.

*

n = 821 for the total cohort, n = 444 for a-eGFR≥60 mL/min/1.73 m2, and n = 377 for a-eGFR<60 mL/min/1.73 m2.

n = 827 for the total cohort; n = 380 for a-eGFR<60 mL/min/1.73 m2.

n = 416 (STEMI patients).

**

comparison between eGFR≥60 and <60 mL/min/1.73 m2.