Table 3.

Discrimination (Area Under the Curve [95% Confidence Interval]) in the Development (IMPACT; n=8428 [Core] and n=6918 [Extended]) and Validation (BTF TBI-trac; n=2513) Data

	Core model	Extended model
Development	0.763 (0.750,0.775)	0.806 (0.794,0.817)
External validation	0.787 (0.765,0.809)	0.827 (0.805,0.845)

Core model: logodds (14-day mortality)=–3.342+0.027 ^* (age)+1.154 ^* (GCS motor score=1)+1.089 ^* (GCS motor=2)+0.642 ^* (GCS motor score=3)+0.225 ^* (GCS motor score=4)+0.707 ^* (GCS motor score=9)+0.780 ^* (pupils=2)+1.567 ^* (pupils=3)

Extended model: logodds (14-day mortality)=−3.957+0.022 ^* (age)+0.990 ^* (GCS motor score=1)+0.861 ^* (GCS motor score=2)+0.522 ^* (GCS motor score=3)+0.166 ^* (GCS motor score=4)+0.424 ^* (GCS motor score=9)+0.625 ^* (pupils=2)+1.488 ^* (pupils=3)+0.282 ^* (hypoxia)+0.752 ^* (hypotension)+0.618 ^* (obliterated cisterns)+0.226 ^* (midline shift)+0.749 ^* (TSAH)

IMPACT, International Mission on Prognosis and Analysis of Clinical Trials in TBI; BTF, Brain Trauma Foundation; GCS, Glasgow Coma Scale; TBI, traumatic brain injury; OR, odds ratio; TSAH, traumatic subarachnoid hemorrhage.