Table 3. Association results for the BP cases and control samples.
| Marker (position) | Sample | LR with covariates | Minor allele (cases - controls) | Odds ratio (95% CI) |
| rs10492555 (35607109) | German GWAS | 0.717 | T (0.15-0.14) | 1.03 (0.86–1.24) |
| Replication | 0.388 | T (0.16-0.15) | 1.05 (0.94–1.18) | |
| All | 0.351 | T (0.16-0.15) | 1.05 (0.95–1.16) | |
| rs7327771 (35577512) | German GWAS | 0.029 * | T (0.07-0.05) | 1.35 (1.03–1.76) |
| Replication | 0.0053 * | T (0.04-0.06) | 0.75 (0.61–0.91) | |
| All | 0.297 | T (0.05-0.05) | 0.90 (0.77–1.06) | |
| rs7994174 (35573018) | German GWAS | 0.032 * | T (0.09-0.07) | 1.29 (1.02–1.63) |
| Replication | 0.047 * | T (0.07-0.08) | 0.82 (0.70–0.97) | |
| All | 0.691 | T (0.07-0.08) | 0.95 (0.83–1.09) | |
| rs7989807 (35523089) | German GWAS | 0.088 | A (0.12-0.10) | 1.20 (0.97–1.48) |
| Replication | 0.864 | A (0.11-0.11) | 1.01 (0.88–1.16) | |
| All | 0.283 | A (0.11-0.11) | 1.07 (0.96–1.20) | |
| rs12874830(35470040) | German GWAS | 0.025 * | C (0.21-0.19) | 1.19 (1.02–1.40) |
| Replication | 0.260 | C (0.21-0.20) | 1.06 (0.95–1.18) | |
| All | 0.027 * | C (0.21-0.19) | 1.10 (1.01–1.20) | |
| rs1171090 (35408728) | German GWAS | 0.043 * | C (0.29-0.26) | 1.16 (1.00–1.34) |
| Replication | 0.324 | C (0.27-0.27) | 0.95 (0.86–1.05) | |
| All | 0.771 | C (0.27-0.27) | 1.01 (0.93–1.10) | |
| rs1171092 (35407728) | German GWAS | 0.046 * | C (0.29-0.26) | 1.15 (1.00–1.34) |
| Replication | 0.496 | C (0.27-0.27) | 0.97 (0.88–1.07) | |
| All | 0.596 | C (0.27-0.27) | 1.02 (0.94–1.11) | |
| rs7990263 (35359216) | German GWAS | 0.874 | T (0.34-0.34) | 0.98 (0.86–1.13) |
| Replication | 0.894 | T (0.35-0.35) | 0.99 (0.91–1.09) | |
| All | 0.852 | T (0.35-0.35) | 1.00 (0.92–1.07) | |
| rs2051090 (35352193) | German GWAS | 0.509 | T (0.45-0.46) | 0.95 (0.84–1.09) |
| Replication | 0.941 | T (0.45-0.45) | 1.01 (0.92–1.10) | |
| All | 0.723 | T (0.45-0.45) | 0.99 (0.92–1.06) | |
| rs1750921 (35350069) | German GWAS | 0.028 * | T (0.22-0.25) | 0.84 (0.72–0.98) |
| Replication | 0.702 | T (0.21-0.21) | 1.01 (0.91–1.13) | |
| All | 0.333 | T (0.22-0.22) | 0.94 (0.86–1.03) | |
| rs1926452 (35342937) | German GWAS | 0.049 * | A (0.13-0.16) | 0.83 (0.69–1.00) |
| Replication | 0.951 | A (0.13-0.13) | 1.00 (0.88–1.13) | |
| All | 0.234 | A (0.13-0.14) | 0.93 (0.84–1.03) | |
| rs10507435 (35338996) | German GWAS | 0.161 | C (0.25-0.27) | 0.89 (0.77–1.04) |
| Replication | 0.532 | C (0.23-0.24) | 0.96 (0.87–1.07) | |
| All | 0.182 | C (0.24-0.25) | 0.93 (0.85–1.01) | |
| rs10507433 (35322698) | German GWAS | 0.558 | A (0.19-0.20) | 0.95 (0.80–1.12) |
| Replication | 0.218 | A (0.19-0.18) | 1.08 (0.95–1.21) | |
| All | 0.514 | A (0.19-0.19) | 1.02 (0.93–1.12) | |
| rs9545424 (35281264) | German GWAS | 0.049 * | T (0.14-0.12) | 1.20 (0.99–1.46) |
| Replication | 0.913 | T (0.12-0.12) | 0.99 (0.87–1.13) | |
| All | 0.222 | T (0.12-0.12) | 1.05 (0.94–1.17) | |
| rs7999483 (35251437) | German GWAS | 0.015 * | G (0.13-0.10) | 1.27 (1.04–1.56) |
| Replication | 0.475 | G (0.10-0.10) | 1.03 (0.90–1.19) | |
| All | 0.048 * | G (0.11-0.10) | 1.10 (0.98–1.23) | |
| rs9545297 (35239668) | German GWAS | 0.028 * | C (0.16-0.14) | 1.22 (1.02–1.46) |
| Replication | 0.714 | C (0.14-0.14) | 1.01 (0.89–1.14) | |
| All | 0.126 | C (0.15-0.14) | 1.07 (0.97–1.18) |
Analyses are presented for both the allelic regression and the genotypic regression for which the genotypes were recoded under an additive genotypic model; age, sex and country/study were used as covariates. The German sample consists of 682 cases and 1300 controls; the replication sample consists of 1814 cases and 2407 controls. The 16 markers that were typed or extracted in the 2 samples are presented (2496 cases and 3707 controls); see Tables S4 and S5 for results from all markers in each sample.
*
indicates significant P-values (<0.05).