Figure 6. Skull and Eustachian tube measurement of Chd7 mutant mice and littermate control mice.

(A, B) Schematic diagrams superimposed on dissected skulls indicate the measured Eustachian tube angles (A) and skull dimensions (B). (C, D) Quantitative evaluation of the Eustachian tube angles and the skull dimensions in mutant and littermate control mice. Mutant mice have larger Eustachian tube angles of both ears than do the littermate control mice. Skull measurements indicated a greater skull height/skull length and nose bone length/skull length ratio in the mutant mice compared to littermate control mice.