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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: In Vivo. 2012 May;26(3):341–354.

Table VII.

Effect of carbamazepine (CBZ) on radiosensitivity of Lewis lung carcinoma in 3LL cells assayed by clonogenic radiation survival curve in vitro.

CBZ Treatment D0 (Gy) ñ
0 μM 2.0±0.4 5.7±2.4
10 μMPre-Irradiation 2.0±0.1 (p=0.9441) 3.3±1.0 (p=0.3520)
10 μM Post-Irradiation 2.0±0.2 (p=0.09522) 3.2±1.3 (p=0.3795)

We evaluated 4-well plates with 500 or 1000 cells per plate irradiated to doses of 0 – 8 Gy. The plates were screened 14 days after irradiation for colonies of >50 cells as described in the Materials and Methods. The p-values compare cell survival of 3LL cell lines treated with CBZ before or after irradiation to those treated with irradiation alone, using linear quadratic or single-hit, multi-target models.