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. Author manuscript; available in PMC: 2012 Apr 24.
Published in final edited form as: Nat Commun. 2011 Oct 4;2:488. doi: 10.1038/ncomms1503

Figure 7. Nuclear transfer into human polyspermic zygotes.

Figure 7

a, Immunocytochemistry of dispermic human zygotes at mitosis. Arrowheads point to pericentrin positive centrosomes, arrows to tubulin positive sperm tails. b, Entry of polyspermic zygotes into mitosis. c, Nuclear transfer into human polyspermic zygotes. Genome removed at mitosis, fusion with a somatic donor cell and chromosome condensation of the somatic cell genome 2h post transfer are shown. d, Cleavage and development after nuclear transfer into polyspermic zygotes. Time indicates the days post fertilization. The arrow points to a birefringent spindle.