Table 2.
Recurrence rate, PFS and OS of patients with stage I and II endometrioid adenocarcinoma of the endometrium based on DNA ploidy
| Variables | Categories | Number of patients (%) | Number of recurrences (%) | Number of deaths (%) | Recurrence site | 5-year recurrence rate ± SE (%) | 5-year PFS | 5-year OS | ||||
| Vagina (%) | Pelvis (%) | Outside pelvis (%) | PFS ± SE % | P-valuea | OS ± SE % | P-valuea | ||||||
| DNA ploidy | Diploid | 728 (78) | 63 (9) | 136 (19) | 29 (46) | 13 (21) | 21 (33) | 8 ± 1 | 85 ± 1 | 0.03 | 90 ±1 | 0.02 |
| Aneuploid (DI ≤1.20) | 118 (13) | 18 (15) | 27 (23) | 9 (50) | 3 (17) | 6 (33) | 14 ± 3 | 81 ± 4 | 89 ± 3 | |||
| Aneuploid (DI >1.20) | 39 (4) | 8 (21) | 14 (36) | 1 (13) | 1 (13) | 6 (75) | 20 ± 7 | 67 ± 8 | 72 ± 7 | |||
| Tetraploid | 52 (6) | 6 (12) | 13 (25) | 2 (33) | 1 (17) | 3 (50) | 12 ± 5 | 83 ± 5 | 85 ±5 | |||
| Total | 937 (100) | 95 (10) | 190 (20) | 41 (43) | 18 (19) | 36 (38) | 10 ± 1 | 84 ± 1 | 89 ± 1 | |||
DI, DNA index; OS, overall survival; PSF, progression-free survival; SE, standard error.
a
Overall P-value by log-rank test.