Table 3.

Stability of Memantine in human plasma samples.

Spiked plasma concentration (pg/ml n = 6)	Concentration measured (pg/ml)	Precision (%CV)	Accuracy (%)
Room temperature stability for 26 hr in plasma
150.00	151.23	1.00	100.82
35000.00	34926.50	0.80	99.79
Three freeze-thaw cycles
150.00	153.02	2.30	102.01
35000.00	34818.00	0.90	99.48
Auto sampler stability for 79 hr
150.00	154.59	1.40	103.06
35000.00	35213.50	0.90	100.61
Stability for 76 days −30°C
150.00	151.53	3.20	101.02
35000.00	35080.50	1.40	100.23