Table 2.

Cancer Cell Growth Inhibitory Activity Comparison of Sesterstatins 1–6 (1–6) Against the Murine P388 Lymphocytic Leukemia (ED₅₀)^a and a Selection of Human Cancer Cell Lines (GI₅₀)^a

Cell Type	Cell Line	1	2	3	4	5	6
Murine Leukemia	P388	0.46	4.2	4.3	4.9	>10	0.17
Pancreas-a	BXPC-3				1.6	2.2	0.44
Melanoma	RPMI-7951					2.1
CNS	U251					1.9
Thyroid ca	KAT-4				2.0		0.40
Thyroid ca	SW1736				2.1		0.87
Lung-NSC	NCI-H460				1.8	2.5	0.18
Pharynx-sq	FADU				2.0	1.9	0.89
Prostate	DU-145				1.6	1.9	0.37

^aED₅₀ and GI₅₀ in μg/mL