Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Inhibition Concentration, IC50(nM), of various Dox compounds
| Compounds | MCF-7 | MDA-MB-231 | MCF-7 (+ES) |
|---|---|---|---|
| Dox | 602 ± 20 | 89 ± 7 | 585 ± 30 |
| Dox-Linker 14 | 597 ± 20 | 86 ± 5 | 594 ± 20 |
| AE-Dox 15 | 11 ± 6 | 90 ± 8 | 589 ± 3 |
The IC50 was estimated by using GraphPad™ 3-parameters curve fitting for 24 h drug exposure data points. All values are represented here, were evaluated in a duplicate of a triplicate count. Standard deviation was measured from the mean of six wells for each compound.
