Table 2.
Diagnostic accuracy of the AQ in MCI and AD
Sensitivity (95% CI) | Specificity (95% CI) | AUC (95% CI) | LR+ (95% CI) | LR− (95% CI) | Cut-off score | |
---|---|---|---|---|---|---|
MCI | 89.00 (81.20–94.40) | 91.00 (83.60–95.80) | 0.95 (0.91–0.97) | 9.89 (9.00–10.80) | 0.12 (0.05–0.30) | 5 ≤ 14 |
AD | 99.00 (94.60–100.00) | 96.00 (90.10–98.90) | 0.99 (0.96–1.00) | 24.75 (23.70–25.90) | 0.01 (0.001–0.09) | 15≤a |
MCI, mild cognitive impairment; AD, Alzheimer's disease.
aCut-off score derived through ROC analysis of MCI and AD cases with AD as outcome and MCI as the reference group; all other values for AD derived using CN as the reference group.