Figure 2.

(a) Varicella protein alignments within DISC1: the boxed regions show the region of alignment, and the blue letters denote 100% identity. This is not an alignment of the whole Varicella proteome but represents fragments of the same or different Varicella proteins that align with DISC1 fragments (vatches). The larger font delineates highly antigenic regions of DISC1 with an antigenicity index of >0.8 (Figure 4). (b) Other viral vatches within the DISC1 protein. The vatches are colour or format coded in relation to the different viruses. (c) Viral vatches for the risk factors implicated in schizophrenia in relation to the highly immunogenic regions of DISC1.