Table 2.
Changes in body composition during treatment.
| Change in body composition | Week 4 | Week 8 | Week 16 | Week 24 | P value ANOVA |
|---|---|---|---|---|---|
| Weight kg | 3.02 ± 0.81∗,a | 4.94 ± 1.08a,b | 7.03 ± 0.97b,c | 8.59 ± 0.97c | <0.0001 |
| 5.5%** | 9.0% | 12.8% | 15.6% | ||
| Fat-free mass kg | 0.93 ± 0.78a | 1.90 ± 0.95a, b | 3.02 ± 0.80b,∗ | 3.53 ± 0.78 | <0.0001 |
| 2.0% | 4.2% | 6.6% | 7.7% | ||
| Body cell mass kg | 0.02 ± 0.95a | 1.65 ± 1.02a,b | 4.00 ± 0.84b,∗ | 4.64 ± 0.93 | <0.0001 |
| 0.0% | 3.5% | 8.5% | 9.9% | ||
| Fat mass kg | 2.09 ± 0.52∗,a | 3.04 ± 0.50a | 4.00 ± 0.59b | 5.05 ± 0.56b | <0.0001 |
| 22.7% | 33.1% | 43.5% | 55.0% |
*different at time point compared to baseline (P < 0.05); variance (±) is standard error.
**percent change is the ratio of the absolute increase at study week divided by the baseline value ×100.
a,b,c values with same superscript (“a” and “a”) are significantly different (adjusted P < 0.05) in pairwise comparisons.