Table 2.
Biodistribution data of 99m Tc-EMB in Balb/c mice. The mice were administered 40 KBq of 99m Tc-INH, and the radioactivity in different organs was measured at 1 hr, 4 hrs, and 24 hrs, respectively. each value is the mean ± SD of three mice and expressed as percentage administered dose per gram organ.
| Organ/Tissue | 1 hour | 4 hours | 24 hours |
|---|---|---|---|
| Blood | 2.0 ± 0.03 | 1.3 ± 0.19 | 0.8 ± 0.02 |
| Heart | 0.73 ± 0.21 | 0.54 ± 0.07 | 0.36 ± 0.6 |
| Lungs | 2.1 ± 0.18 | 1.88 ± 0.3 | 1.05 ± 0.04 |
| Liver | 5.5 ± 0.5 | 7.0 ± 0 | 3.83 ± 0.21 |
| Spleen | 1.41 ± 0.09 | 1.78 ± 0.43 | 1.04 ± 0.02 |
| Intestine | 6.21 ± 0.4 | 6.99 ± 0.17 | 2.09 ± 0.03 |
| Kidney | 10.3 ± 0.42 | 11.35 ± 0.32 | 2.02 ± 0.04 |
| Muscle | 1.6 ± 0.2 | 1.0 ± 0.2 | 1.68 ± 1.1 |
| Bone | 1.08 ± 0.28 | 0.88 ± 1 | 0.64 ± 0.05 |
| Brain | 0.165 ± 0.06 | 0.07 ± 0.19 | 0.06 ± 0.2 |
| Stomach | 1.01 ± 0.31 | 0.8 ± 1 | 1.0 ± 0.3 |