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. 2012 May 1;86(5):782–788. doi: 10.4269/ajtmh.2012.11-0520

Table 4.

Distribution of mutant alleles of dhfr, dhps, Pfcrt, and Pfmdr among P. falciparum isolates from Jazan among Saudi and non-Saudi patients

dhfr alleles dhps alleles Pfcrt alleles Pfmdr1 alleles
51N 51I 108S 108N 437A 437G 74M/75N/76K 74I/75E/76T 86N 86Y 184Y 184F
Saudi
 Resident 89 46 88 47 135 0 0 123 89 39 3 123
 Visitors 6 0 5 1 7 0 0 7 6 0 1 6
 Total 95 46 93 48 143 0 0 130 95 39 4 129
Expatriates
 Resident 5 2 5 2 8 1 0 9 7 2 0 8
 Visitors 18 10 18 10 28 0 2 23 16 10 1 22
 Total 23 12 23 12 36 1 2 32 23 12 1 30
Total 118 58 116 60 178 1 2 162 118 53 5 160
 Total 176 176 179 164 171 165
 χ2* 0.001 0.012 NC NC 0.839 1.254
 P value 0.978 0.914 NC NC 0.36 0.534
 OR§ 0.989 1.043 NC NC 0.693 1.032
*

Degree of freedom (df) for all χ2 = 1 except for Pfmdr1/184 allele (df = 2).

Not calculated (NC), because the sample was less than two in either resistant (dhps) or sensitive (Pfcrt) alleles.

P values in calculated alleles were > 0.05; thus, all are non-significant, and all hypotheses are accepted.

§

OR calculated at 95% confidence interval.