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. 2012 May 1;86(5):812–820. doi: 10.4269/ajtmh.2012.11-0458

Figure 2.

Figure 2.

Clinical evolution from the 7th to 45th day after birth of offspring born to hamster mothers infected at the chronic phase of the infection with Leishmania donovani (CHR-offs) or born to mothers infected during pregnancy (AC-offs) compared with offspring born to uninfected mothers (CTR-offs). A, Body weight at the end of lactation (21 days of birth) and after weaning at 45 days of age; CHR-offs and AC-offs had body weights similar to CTR-offs during lactation; after weaning, CHR-offs (n = 96) weighed significantly less than AC-offs (n = 68) or CTR-offs (n = 55) (**P < 0.001 each, by Tukey-Kramer multiple comparisons test). B, Mortality of AC-offs and CHR-offs infected with L. panamensis (L.p.) or L. donovani (L.d.) was higher than that of controls (CTR-offs) (L. panamensis AC-offs, n = 104, P = 0.001; L. panamensis CHR-offs, n = 79, P = 0.0014; L. donovani AC-offs, n = 109, P < 0.0001; L. donovani CHR-offs, n = 47, P = 0.019; CTR-offs, n = 162, by Fisher's exact test). C, Hematocrit at 45 days of age; L. donovani CHR-offspring (n = 52) had significantly lower hematocrit than L. donovani AC-offs (n = 40; ***P < 0.0001, by Mann-Whitney test) or CTR-offs (n = 20) (**P = 0.0045, by Mann-Whitney test).