Table 2.
Regression coefficients and associated statistics.
| Predictors | Coefficient | SE | t | P | 95% CI | |
|---|---|---|---|---|---|---|
| Lower | Upper | |||||
| Age (y) | −0.0030 | 0.0027 | −1.12 | .26 | −0.0083 | 0.0023 |
| background (IU/mL) | 0.57 | 0.089 | 6.46 | <.0005 | 0.40 | 0.75 |
| Mitogen background (IU/mL) | 0.016 | 0.0056 | 2.78 | .006 | 0.0046 | 0.027 |
| Albumin (g/dL) | 0.0055 | 0.11 | 0.05 | .96 | −0.21 | 0.22 |
| Hemoglobin (g/dL) | −0.023 | 0.029 | −0.79 | .43 | −0.080 | 0.034 |
| Neutrophil (1000/mm3) | −0.14 | 0.021 | −6.51 | <.0005 | −0.18 | −0.095 |
| Monocyte (1000/mm3) | 0.26 | 0.23 | 1.13 | .26 | −0.19 | 0.72 |
| Lymphocyte (1000/mm3) | 0.61 | 0.13 | 4.65 | <.0005 | 0.35 | 0.87 |
| Eosinophil (1000/mm3) | −0.63 | 0.44 | −1.43 | .15 | −1.5 | 0.23 |
| CRP (mg/dL) | −0.015 | 0.012 | −1.27 | .21 | −0.038 | 0.0081 |
| AST (IU/L) | −0.0023 | 0.0030 | −0.76 | .45 | −0.0082 | 0.0036 |
| ALT (IU/L) | 0.0047 | 0.0032 | 1.48 | .14 | −0.0015 | 0.011 |
| Creatinine (mg/dL) | 0.18 | 0.12 | 1.48 | .14 | −0.058 | 0.41 |
| Mitogen × Lymphocyte | −0.0073 | 0.0034 | −2.16 | .031 | −0.014 | −0.00067 |
| Intercept (ln IU/mL) | 0.22 | 0.47 | ||||
Note. Regression coefficients for linear regression of log-transformed antigen-stimulated IFN-γ production by the QuantiFERON-TB Gold. Wald (t) test statistics are based upon 698 degrees of freedom. P values are not adjusted for multiplicity. Diagnostic plots do not indicate significant departures from normality for the distribution of residuals or nonlinearity in the predictions. The maximum variance inflation factor (<4) is within an acceptable range. CRP: C-reactive protein; AST: aspartate amino transferase; ALT: alanine aminotransferase; SE: standard error; CI: confidence inter.