Table 3.
Analysis of area under the receiver operating characteristic curves for lymphocyte-stratified patients groups.
| Lymphocyte count/mm3 | n | AUROC curve | 95% CI | SE | cutoff value IU/mL | sensitivity % | 95% CI | specificity % | 95% CI |
|---|---|---|---|---|---|---|---|---|---|
| <300 | 45 | 0.86 | 0.777–0.943 | 0.04 | 0.04 | 80 | 65.4–90.4 | 86 | 81.7–89.2 |
| 300–500 | 57 | 0.82 | 0.806–0.938 | 0.03 | 0.04 | 79 | 66.1–88.6 | 86 | 81.7–89.2 |
| 500–700 | 79 | 0.93a | 0.883–0.973 | 0.02 | 0.05 | 89 | 81.0–95.5 | 89 | 85.7–92.4 |
| 700–1000 | 145 | 0.97b | 0.962–0.987 | 0.01 | 0.1 | 87 | 80.3–91.9 | 94 | 91.2–96.3 |
| 1000–1200 | 98 | 0.98b | 0.957–0.994 | 0.01 | 0.1 | 91 | 83.3–95.7 | 94 | 91.2–96.3 |
| 1200–1500 | 121 | 0.97b | 0.954–0.993 | 0.01 | 0.1 | 93 | 87.4–97.1 | 95 | 91.8–96.8 |
| 1500–1800 | 78 | 0.97b | 0.949–0.989 | 0.01 | 0.15 | 91 | 82.4–96.3 | 96 | 93.2–97.6 |
| >1800 | 104 | 0.99b | 0.992–0.9997 | 0.002 | 0.19 | 96 | 90.4–98.9 | 98 | 96.0–99.2 |
Note. AUROC: area under the receiver operating characteristic; SE: standard error; CI: Confidence Interval Categories for lymphocyte counts exclude the value shown for the upper end of the range.
a: P < .05 versus <300/mm3 category and P < .05 versus 300–500/mm3 category.
b: P < .05 versus <300/mm3 category, P < .05 versus 300–500/mm3 category, and P < .05 versus 500–700/mm3 category.