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. 2012 Apr 24;7(4):e35710. doi: 10.1371/journal.pone.0035710

Figure 2. HSA/TIMP-2 inhibits tumor cell proliferation but not apoptosis in prostate tumors.

Figure 2

(A) Representative immunohistochemical images of Ki-67 and active caspase-3 immunohistochemistry. Tumor sections were obtained at 15 days after initial injection of 80 mg/kg HSA/TIMP-2 (n = 4 per group). The representative images were taken at an original magnification of 200×. (B) Quantification of Ki67- and active caspase-3-positive cells as expressed by the percentage of brown pixels per field. The quantitative data represent the mean ± SEM (n = 4 per group). Significant difference compared to the control group: * P<0.05 by Student's t test. ns = non-significant.