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. 2012 Apr 24;7(4):e35583. doi: 10.1371/journal.pone.0035583

Table 6. Correlation coefficients (r) between muscle mRNA expression of several cis- and trans- regulated genes and intramuscular fat content, fatty acid profile and cholesterol content of the gluteus medius muscle.

High group2 Low group2 Whole dataset2
Regulated gene QTL trait1 R P-value r P-value r P-value
DNAJB6 Linoleic FA −0.08 0.5729 −0.30 0.0339 −0.18 0.0670
HOXA10 Palmitoleic FA 0.39 0.0037 0.01 0.9643 0.19 0.0526
Linoleic FA 0.35 0.0100 −0.22 0.1250 0.08 0.4191
Stearic FA −0.32 0.0227 −0.09 0.5429 −0.21 0.0388
cis- acting IL12RB2 IMF 0.37 0.0062 0.16 0.2565 0.32 0.0008
eQTL Muscle Cholesterol 0.16 0.2377 −0.31 0.0261 0.13 0.1713
NEDD4L Myristic FA 0.28 0.0367 0.30 0.0310 0.33 0.0006
Palmitoleic FA 0.28 0.0425 −0.04 0.7929 −0.03 0.7984
NUDT6 Palmitic FA 0.04 0.7829 −0.33 0.0293 −0.14 0.1602
PPP1CB Palmitic FA 0.29 0.0380 −0.13 0.4082 0.14 0.1712
Linoleic FA −0.22 0.1035 0.36 0.0099 −0.02 0.8783
ACACA IMF 0.15 0.2669 0.43 0.0016 0.42 0.0001
ACLY IMF −0.02 0.8688 0.31 0.0248 0.18 0.0623
Palmitic FA 0.04 0.7942 0.37 0.0123 0.23 0.0264
CAST Palmitoleic FA −0.32 0.0189 −0.25 0.0713 −0.32 0.0010
Myristic FA 0.25 0.0708 −0.29 0.0381 0.09 0.3623
Linoleic FA −0.23 0.0832 0.35 0.0107 −0.06 0.5432
Palmitic FA 0.31 0.0297 −0.04 0.7828 0.22 0.0310
CS Palmitoleic FA 0.29 0.0318 −0.03 0.8497 0.15 0.1237
Linoleic FA 0.39 0.0039 −0.33 0.0188 0.07 0.4947
CYP24A1 Palmitic FA 0.25 0.0468 0.38 0.0108 0.26 0.0100
trans- acting Muscle Cholesterol −0.32 0.0172 −0.34 0.0134 −0.17 0.0890
eQTL FABP5 Palmitoleic FA −0.41 0.0023 0.18 0.2045 0.05 0.6454
Linoleic FA −0.35 0.0086 0.12 0.4153 0.07 0.4594
Stearic FA 0.44 0.0014 0.01 0.9986 0.15 0.1449
Muscle Cholesterol −0.27 0.0453 0.05 0.7523 −0.12 0.2088
LRP6 Palmitoleic FA 0.27 0.0444 0.08 0.5585 0.08 0.4374
Myristic FA 0.01 0.9834 0.31 0.0286 0.16 0.1023
Linoleic FA 0.24 0.0859 −0.41 0.0027 −0.15 0.1392
RRM2B Linoleic FA −0.29 0.0312 0.40 0.0032 0.04 0.6706
Stearic FA 0.29 0.0385 0.05 0.7690 0.18 0.0755
YWHAZ Palmitoleic FA 0.33 0.0148 0.21 0.1494 0.28 0.0040
Linoleic FA 0.33 0.0151 −0.17 0.2205 0.11 0.2434
1

IMF – intramuscular fat content; FA – Fatty Acid content (%).

2

Significant correlation coefficients are indicated in bold.