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. 2012 Apr 24;7(4):e35094. doi: 10.1371/journal.pone.0035094

Figure 8. VEGF-D secreted by 468LN cells promotes migration and invasion by HMVEC-dLy cells:

Figure 8

Significant stimulation of both migration and invasion of HMVEC-dLy cells occurred in the presence of 468LN conditioned medium (CM), as compared to 468GFP CM. This stimulation was significantly attenuated by VEGF-D knock down (KD) in 468 LN, which could be restored with exogenous rVEGF-D. For VEGF-D knock down, data were normalised to scrambled siRNA (SCR-KD), and for rVEGF-D stimulation, data were normalised to VEGF-D knock down. Data represent mean (n = 4) ± SE. *,P<0.05; **,P<0.01.