Table 3. Results from gene set analysis using the EDS as the query gene list. Enrichment scores are as described above.
Dataset | GEO # | SSc-PH-ILD | IPAH | SSc-PAH | SSc | PAH | IPF-PH | CBvAB |
JHU | GSE33463 | 33.327 | 21.082 | 17.886 | 2.688 | - | - | - |
Risbano et al.14 | GSE22356 | - | 26.019 | 7.553 | −15.476 | - | - | - |
Pendergrass et al.13 | GSE19617 | - | - | 15.004 | 9.247 | - | - | - |
Bull et al.11 | GSE703 | - | 7.736 | - | - | - | - | - |
Rajkumar et al.31 | GSE15197 | - | - | - | - | 4.083 | −1.337 | - |
Goh et al.32 | GSE6236 | - | - | - | - | - | - | 7.811 |
In all cases data was downloaded from the NCBI Gene Expression Omnibus (GEO) website as processed by the submitter and published by GEO as a Series Matrix File. Phenotype labels: Interstitial Lung Disease (SSC-PH-ILD), Idiopathic Arterial Hypertension (IPAH), Scleroderma with Pulmonary Arterial Hypertension (SSc-PAH), Scleroderma (SSc), Pulmonary Arterial Hypertension only (PAH), Idiopathic Pulmonary Fibrosis with Pulmonary Hypertension (IPF-PH), and human Cord Blood versus human Adult Blood (CBvAB).