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. 2001 Jan 16;98(2):392–394. doi: 10.1073/pnas.98.2.392

Figure 1.

Figure 1

The interrelationship of cancer genetics and epigenetics. Rather than a traditional Venn diagram, cancer genetics and epigenetics are drawn as a yin-yang. For example, loss of imprinting might be caused by genetic disruption of CTCF or by altered methylation of the DMR (illustrated). Other examples of overlap or in which the distinction between genetics and epigenetics are blurred are provided in the text.