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The distribution of 5-hydroxymethyl-cytosine in adult Xenopus (A) and axolotl (B and C) tissues. 5-hydroxymethylcytsoine and 5-methyl-cytosine have been detected in indicated tissues using 1:5,000 dilution of anti-5-hmC antibody. Immunostaining for 5-hmC, 5-mC and merge views are shown. Skel muscle-skeletal muscle. Scale bars are 20 µm.
