FIGURE 3. Amphetamine treatment for eight days increases phosphorylation of Akt and reduces phosphorylation of GSK3 in the hippocampus.
A. Hippocampal Thr308-Akt phosphorylation was increased after 2 mg/kg amphetamine treatment for eight days. B. Hippocampal Ser21-GSK3α and Ser9-GSK3β phosphorylation was increased after administration of amphetamine for eight days. Values are presented as percent of matched control mice. Means ± SEM. n=3. *, p≤0.05.